GreeneryBio
Salicin

Salicin

Product Name: Salicin (White Willow Bark Extract) Synonym Name: 2-(Hydroxymethyl)phenyl β-D-glucopyranoside; Salicoside CAS Number: 138-52-3 Molecular Formula: C₁₃H₁₈O₇ Molecular Weight: 286

Chemical identity

CAS Number
138-52-3
Molecular Formula
C13H18O7
Molecular Weight
286.28g/mol
Appearance
White to off-white fine powder (high purity); Brown to light-yellow powder (low

Empirical formula

C13H18O7

MW 286.28 · CAS 138-52-3

MOQ
1 kg
Lead Time
7-15 business days

Certifications

ISO 9001ISO 22000

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Product Description

Introduction of Salicin

Salicin, a natural phenolic β-glucoside and precursor of aspirin, is mainly extracted from the bark of Salix alba L. Our Salicin is sourced from pollution-free-grown white willow bark (3-5 years old for high active ingredient content) and extracted via an eco-friendly, GMP-certified process (ultrasonic-assisted extraction + multi-stage resin adsorption) with food-grade ethanol, ensuring safety and bioactivity.

We offer customizable purity specifications (≥70%, ≥80%, ≥90%, main specification ≥98% by HPLC), exceeding industry averages. Differentiated advantages: milder than synthetic salicylic acid derivatives (lower gastrointestinal irritation, higher biocompatibility), higher purity and stable quality than other extracts, 30% shorter production cycle, 40% less pollution, and optional enteric-coated formulations (40% higher bioavailability).

Key Active Compounds

Core compound: Salicin (CAS No.: 138-52-3, C₁₃H₁₈O₇, MW 286.28), a white crystalline powder soluble in water, ethanol, DMSO and dimethylformamide (melting point 207 °C, decomposition at 240 °C).

Trace synergistic compounds (naturally derived): Salicortin & Tremulacin (enhance anti-inflammatory effects), flavonoids (antioxidant synergism), and salicyl alcohol (hydrolytic product converted to salicylic acid).

Benefits

Anti-inflammatory & Analgesic Effects

Inhibits COX-1/COX-2 to supports normal inflammatory response and mild-to-moderate pain (arthritis, muscle soreness, headaches, etc.), with long-lasting effects and lower gastrointestinal risk than synthetic NSAIDs.

Antipyretic Effect

Mildly reduces fever by acting on the hypothalamic thermoregulatory center, safe for all ages (excluding allergies).

Anti-rheumatic Effect

Adjunctively relieves rheumatic conditions (osteoarthritis, rheumatoid arthritis), improving joint function and delaying damage.

Skin Care Benefits

Promotes skin metabolism, mild exfoliation, reduces pigmentation and acne, suitable for sensitive skin.

Other Potential Benefits

Mild anti-platelet aggregation (weaker than aspirin) for cardiovascular health, and antioxidant effects to reduce cellular oxidative damage.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Technical Specifications

ParameterValueMethod
ItemSpecificationTest Method
Product NameSalicin
Plant SourceBark of _Salix alba_ L.Microscopic Identification
AppearanceWhite Crystalline PowderVisual Inspection
Purity (Salicin)≥98% (Customizable: ≥70%, ≥80%, ≥90%)HPLC
Loss on Drying≤5.0%USP <731>
Ash Content≤3.0%USP <281>
Heavy Metals≤10 ppmAtomic Absorption Spectroscopy
Pesticide ResidueConforms to USP/NF StandardsGC-MS
Microbial LimitTotal Aerobic Microbes ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli: NegativeUSP <61> & <62>
CAS No.138-52-3
Molecular FormulaC₁₃H₁₈O₇
Melting Point205-209 °CUSP<741>

Full batch-specific COA available on request.

Commercial Terms

MOQ
1 kg
Lead time
7-15 business days
Shelf life
24 months unopened
Sample
On request
Packaging
1 kg aluminum foil bag · 25 kg fiber drum
Storage
Sealed, cool, dry, light-protected