Introduction
Botanical Source & Raw Material Quality
Our Rutin is exclusively extracted from Sophora japonica L. (Japanese Pagoda Tree) buds, a time-honored botanical source renowned for its exceptional rutin concentration (23-25% in dried buds). We maintain strict sourcing protocols, partnering with GAP-certified plantations in China and Korea that practice sustainable cultivation without pesticides or chemical fertilizers. This ensures a consistent, high-quality raw material base that meets global organic standards.
Advanced Extraction & Purification Process
We employ a proprietary alkali extraction-acid precipitation combined with membrane separation technology, optimized for maximum rutin retention and purity:
- Pre-treatment: Raw buds undergo low-temperature drying and micro-pulverization to preserve bioactivity
- Extraction: pH-controlled alkaline solution extraction at 60-70°C with ultrasonic assistance to enhance yield by 25%
- Purification: Multi-stage filtration (microfiltration + ultrafiltration) removes plant fibers, proteins, and colloids
- Precipitation: Acidification under precise temperature control (5-10°C) to form pure rutin crystals
- Drying: Vacuum freeze-drying to maintain structural integrity and prevent thermal degradation
- Quality Assurance: HPLC fingerprinting throughout the process ensures batch-to-batch consistency
Potency & Standardization
Our Rutin is standardized to ≥95% purity (HPLC), with premium grades available at 98% and 99% purity. Each batch undergoes rigorous testing to confirm active compound concentration, ensuring compliance with NF11, USP43, and EP9 pharmacopeial standards.
Unique Differentiation Advantages
- Superior Bioavailability: Specially formulated microcrystalline particles (D90 ≤ 10μm) enhance dissolution rate by 40% compared to conventional rutin
- Low Impurity Profile: Total heavy metals <10ppm, residual solvents <500ppm, and microbiological counts meeting pharmaceutical-grade requirements
- Sustainability Commitment: 100% renewable energy-powered production and zero-waste water treatment systems
- Traceability: Blockchain-enabled supply chain tracking from seed to finished product
- Customization: Tailored particle size, solubility, and formulation options (powder, granule, or liquid) to meet specific application needs
Key Active Compounds
| Compound | Chemical Formula | Molecular Weight | Content | CAS Number |
|---|---|---|---|---|
| Rutin (Quercetin-3-rutinoside) | C₂₇H₃₀O₁₆ | 610.52 g/mol | ≥95% | 153-18-4 |
| Quercetin (minor metabolite) | C₁₅H₁₀O₇ | 302.23 g/mol | ≤2% | 117-39-5 |
| Isoquercitrin | C₂₁H₂₀O₁₂ | 464.38 g/mol | ≤1% | 482-35-9 |
| Kaempferol glycosides | C₂₇H₃₀O₁₅ | 594.52 g/mol | ≤0.5% | N/A |
Our Rutin is characterized by its high quercetin-3-rutinoside specificity (>98% of total flavonoids), distinguishing it from lower-grade products containing significant amounts of other flavonoid derivatives. The presence of minor quercetin metabolites enhances synergistic biological activity while maintaining product purity.
Benefits
Cardiovascular Health Support
Powerful Antioxidant & Anti-Inflammatory Effects
Metabolic & Immune Support
Physical & Chemical Properties
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | Yellow to greenish-yellow crystalline powder | Visual inspection |
| Odor | Characteristic, slightly aromatic | Olfactory test |
| Melting Point | 195-205°C (decomposition) | DSC |
| Solubility | Slightly soluble in water (0.125g/L at 20°C), soluble in methanol and alkaline solutions | Solubility test |
| Loss on Drying | ≤8.0% | USP <731> |
| Ash Content | ≤0.5% | USP <281> |
| Particle Size | D90 ≤ 10μm (standard grade), customizable | Laser diffraction |
| pH (1% solution) | 5.0-7.0 | pH meter |
Assay & Purity
| Parameter | Specification | Test Method |
|---|---|---|
| Rutin Content | ≥95.0% (98%/99% grades available) | HPLC (USP <621>) |
| Quercetin | ≤2.0% | HPLC |
| Total Flavonoids | ≥98.0% | UV spectrophotometry |
| Heavy Metals | Pb <2ppm, Cd <1ppm, As <1ppm, Hg <0.1ppm | ICP-MS |
| Residual Solvents | ≤500ppm | GC-MS |
| Microbiological Limits | Total Aerobic Count <1,000cfu/g, Yeast/Mold <100cfu/g, E. coli absent, Salmonella absent | USP <61>/<62> |
Packaging & Storage
- Packaging: 1kg aluminum foil bags, 25kg fiber drums with double plastic liners
- Shelf Life: 36 months from manufacturing date when stored properly
- Storage Conditions: Store in a cool (15-25°C), dry place, protected from light and moisture
Application Cases
Pharmaceutical Industry
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Vascular Health Formulations:
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Anti-Diabetic Complications:
Nutraceutical & Functional Foods
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Cardiovascular Supplements:
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Sports Nutrition:
Cosmetics & Personal Care
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skin wellness support Serums:
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Sunscreen Formulations:
Food & Beverage Industry
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Functional Beverages:
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Bakery Products:
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.







