GreeneryBio
Natto Extract

Natto Extract

Product Name: Natto Extract CAS No

Chemical identity

CAS Number
133876-92-3
Appearance
Light yellow-white fine powder, no visible impurities Mesh: 80-100 mesh (custom
MOQ
1 kg
Lead Time
7-15 business days

Certifications

ISO 9001ISO 22000

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Product Description

Introduction

Natto Extract is a high-value natural active ingredient derived from natto, fermented by Bacillus subtilis var. natto. We implement strict quality control from raw material selection to extraction, ensuring bioactive retention and stability.

Raw Material Source: We select non-GMO soybeans from pollution-free Chinese planting bases (Shandong, Jiangsu), complying with GB 1352 standards, free from pollutants. Strict sorting, cleaning and sterilization ensure raw material safety.

Extraction Process: Advanced low-temperature integrated process (enzyme-assisted extraction, ultrafiltration, membrane separation, freeze-drying) retains nattokinase activity. Purification removes impurities, vitamin K2 and purines, with GMP and ISO22000 certification for stable batch consistency.

Active Ingredient Content: Nattokinase (NK) activity: 2000-4000 FU/g (conventional), up to 40000 FU/g (high-purity); total isoflavones ≥8% (aglycones ≥30%); active peptides ≥15%, meeting global high standards.

Differentiation Advantages: Core advantages: high NK activity retention (≥95% in 24 months); high purity (no vitamin K2/purines, low heavy metals); acid resistance for high bioavailability; multi-component synergy of active substances.

Key Active Compounds

Our Natto Extract contains proven bioactive compounds:

  • Nattokinase (NK): A serine protease (275 amino acids, 27724 molecular weight) with strong fibrinolytic activity (FU unit), specifically decomposing fibrin without damaging blood vessels/cells.

  • Soybean Isoflavones: ≥8% total content (14 isomers), with increased absorbable aglycones, offering weak estrogen-like, antioxidant and anti-glycation effects.

  • Active Peptides: ≥15% content, small-molecule, easily absorbable, aiding physiological regulation, gastrointestinal health and immunity.

  • Vitamins and Minerals: Rich in vitamin B2, calcium, iron and potassium, supplementing essential nutrients.

Benefits

Our Natto Extract offers multiple science-backed health benefits:

  • Cardiovascular Health Support: NK decomposes fibrin clots, reduces blood viscosity, with no side effects of synthetic anticoagulants.

  • Antioxidant and skin wellness support: Isoflavones and active peptides scavenge free radicals, inhibit matrix-degrading enzymes, delaying skin aging.

  • Anti-Glycation and Metabolic Regulation: Isoflavones inhibit advanced glycation end products (AGEs), aiding glucose metabolism.

  • Gastrointestinal Health Improvement: Active peptides promote beneficial intestinal bacteria, enhancing digestion and absorption.

  • Bone Health Protection: Isoflavones + calcium promote calcium absorption, maintaining bone density.

  • Immunity Enhancement: Active peptides stimulate immune cell proliferation, boosting resistance.

Application Cases

Our Natto Extract is widely used in multiple fields with mature global cases:

  • Dietary Supplements: Cooperated with Biofermin (Japan) and NattoPharma (USA) to develop NK softgels/capsules/tablets (100-200mg daily), certified EU USDA Organic/Kosher/Halal, annual sales over 10 million bottles.

  • Functional Foods: Added (0.5-1.0%) to beverages, protein bars and dairy products; a domestic beverage achieved 500,000 monthly sales via its natural health attributes.

  • Cosmetics: Cooperated with international brands for skin wellness support serums/masks (1-2% addition), improving wrinkles and dullness with stable performance.

  • Pharmaceutical Intermediates: Provided high-purity extract (NK≥30000 FU/g) for anti-thrombotic drug R&D, meeting USP32 standards.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Technical Specifications

ParameterValueMethod
ItemSpecificationTest Method
AppearanceLight yellow to brown fine powder, no visible impuritiesVisual Inspection
Odor & TasteCharacteristic natto odor, no off-flavorSensory Evaluation
Nattokinase Activity2000-40000 FU/g (Customizable)UV Spectrophotometry (Q/HZD 0078S-2022)
Total Isoflavones≥8%UPLC-ESI-MS/MS
Active Peptides≥15%Biuret Method
Moisture/Ash≤10.0% eachGB 5009.3/4
Heavy MetalsAs≤0.5, Pb≤0.8, Cd≤0.5 mg/kg; Hg≤1 ppmGB 5009.11/12
Microbial LimitsTotal Plate Count≤30000 CFU/g; Salmonella: Negative/25gGB 4789 Series
Mesh Size/Storage95% pass 80 mesh; 24 months (sealed, cool dry)Sieve Analysis/-

Full batch-specific COA available on request.

Commercial Terms

MOQ
1 kg
Lead time
7-15 business days
Shelf life
24 months unopened
Sample
On request
Packaging
1 kg aluminum foil bag · 25 kg fiber drum
Storage
Sealed, cool, dry, light-protected