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Rice Phytoceramide

Rice Phytoceramide

CAS No

Chemical identity

CAS Number
100403-19-8
Appearance
Off-white/light yellow loose powder; high purity: white crystalline, odorless, g
MOQ
1 kg
Lead Time
7-15 business days

Certifications

ISO 9001ISO 22000

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Product Description

Introduction

Rice Phytoceramide, a natural lipid from Oryza sativa L. rice bran, is a high-value active ingredient widely used in cosmetics, functional foods and pharmaceuticals. As a plant-derived alternative to synthetic and animal-sourced ceramides, it features superior safety, biocompatibility and efficacy for high-end formulations.

Raw Material Source: Extracted from high-quality non-GMO rice bran, sourced from pollution-free bases with strict quality control to avoid heavy metals and pesticides. Optional sea red rice bran (salt-tolerant) is available for enhanced bioactivity due to higher minerals and lipids.

Extraction Process: Adopting GMP-compliant, eco-friendly co-fermentation (yeast & lactic acid bacteria) + ultrasonic-assisted ethanol extraction. Key steps: pretreatment, co-fermentation (30-37℃, 5-7 days), ultrasonic extraction, purification and quality inspection. It avoids harmful solvents, retains bioactivity, with an extraction yield up to 12.54%.

Active Ingredient Content: Customizable glucosylceramide (main active form) content: 1%-10% (standard), up to 98% (high-purity). HPLC-tested for accuracy (CV ≤ 5%), with trace synergistic ingredients like β-sitosterol glucoside.

Differentiation Advantages: Compared with synthetic/other plant ceramides,

  • High biocompatibility (similar to human skin ceramides, no irritation);
  • 100% plant-derived, non-GMO, certified by ISO/FDA/Halal/Kosher;
  • Multi-efficacy (moisturizing, skin wellness support, anti-allergic);
  • Stable performance (soluble in ethanol/water, pH 4.0-8.0, ≤80℃);
  • Cost-effectiveness from advanced process and abundant raw materials.

Key Active Compounds

Core active components are natural glucosylceramides (GlcCer) and derivatives, composed of sphingoid bases and fatty acids. Key compounds:

  • Glucosylceramides (GlcCer): 70-85% of total content, main subtypes include Cer 18:0/24:0 (2OH) and Cer 18:0/26:0. Responsible for moisturizing, barrier repair and skin wellness support, convertible to free ceramides in the human body.

  • Phytosphingosine (PS): 5-10% of total, with antibacterial/anti-inflammatory effects, regulating skin cell function and enhancing barrier.

  • Sphingosine (S) & Dihydrosphingosine (DS): 3-5% total, synergizing with GlcCer to improve hydration and elasticity.

  • Synergistic Ingredients: β-sitosterol glucoside, linoleic acid, etc., enhancing solubility, absorption and auxiliary efficacy.

Benefits

Rice Phytoceramide offers proven multi-dimensional skin benefits, supported by in vitro/in vivo/clinical studies, applicable to multiple fields:

Skin Health Benefits (Topical & Oral)

  • Intensive Moisturizing & Barrier Repair: Reduces TEWL by 30-50%, improves hydration by 40-60%, repairs barriers damaged by aging/environment, relieving dryness.

  • Anti-Acne & Soothing: Regulates skin immunity, supports normal inflammatory response, suitable for sensitive skin, cutting cosmetic-related allergy risk by over 70%.

  • Depigmentation & Brightening: Reduces melanin/erythema index, improves dullness via inhibiting melanin synthesis and promoting cell renewal.

Other Potential Benefits

  • Oral Health Support: Improves oral mucosa moisture, relieves dry mouth and reduces oral ulcers.

  • Immune Regulation: Preliminary studies suggest regulatory effects, requiring further clinical confirmation.

Application Cases

Widely applied in cosmetics, functional foods and pharmaceuticals. Typical cases:

Cosmetics Field

  • Moisturizing Serum: 3% Rice Phytoceramide + hyaluronic acid/glycerin; relieves dryness/sensitivity, 85% user improvement in 2 weeks.

  • skin wellness support Cream: 5% Rice Phytoceramide + retinol/squalane; reduces wrinkles by 25-30% and improves firmness by 35% in 8 weeks.

  • Sensitive Skin Lotion: 2% Rice Phytoceramide + centella asiatica/panthenol; soothes redness and strengthens barriers.

Functional Food Field

  • Oral Tablets: 40mg Rice Phytoceramide/tablet + collagen/vitamin C; reduces TEWL by 35% and melanin by 20% in 12 weeks.

  • Oral Liquid: 20mg/10mL Rice Phytoceramide + honey; relieves dry skin/mouth.

Pharmaceutical Field

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Technical Specifications

ParameterValueMethod
ItemSpecificationTest Method
Product NameRice Phytoceramide
Botanical SourceBran of _Oryza sativa L._TLC
Active Content1%-10% (GlcCer), up to 98% availableHPLC
AppearanceLight yellow to off-white fine powderVisual Inspection
Moisture/Ash Content≤5.0% eachUSP
Particle Size≥95% through 80 mesh (customizable)USP
Heavy MetalsTotal ≤10 ppm; Pb ≤2.0 ppm; Cd ≤1.0 ppm; As ≤2.0 ppm; Hg ≤1 ppmICP-MS
MicrobiologyTotal Plate Count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli/Salmonella: NegativeUSP 34
Solubility/pHSoluble in ethanol/propylene glycol/water; pH 4.0-8.0 (1% solution)Visual/pH Meter
Storage Period/CAS No.24 months; 104404-17-3

Full batch-specific COA available on request.

Commercial Terms

MOQ
1 kg
Lead time
7-15 business days
Shelf life
24 months unopened
Sample
On request
Packaging
1 kg aluminum foil bag · 25 kg fiber drum
Storage
Sealed, cool, dry, light-protected